Anti-c-Met antibodies recognising a temperature sensitive epitope, inhibit cell growth
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چکیده
منابع مشابه
Anti-c-Met antibodies recognising a temperature sensitive epitope, inhibit cell growth
c-Met is a tyrosine receptor kinase which is activated by its ligand, the hepatocyte growth factor. Activation of c-Met leads to a wide spectrum of biological activities such as motility, angiogenesis, morphogenesis, cell survival and cell regeneration. c-Met is abnormally activated in many tumour types. Aberrant c-Met activation was found to induce tumour development, tumour cell migration and...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2013
ISSN: 1949-2553
DOI: 10.18632/oncotarget.1075